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A preliminary clinico-epidemiological portrayal of COVID-19 pandemic at a premier medical institution of North India.
Annals of Thoracic Medicine ( IF 2.1 ) Pub Date : 2020-07-01 , DOI: 10.4103/atm.atm_182_20 Sudhir Bhandari 1 , Ajit Singh Shaktawat 1 , Raman Sharma 1 , Amitabh Dube 2 , Shivankan Kakkar 3 , S Banerjee 1 , Prakash Keshwani 1 , Shrikant Sharma 1 , Sunil Mahavar 1 , C L Nawal 1 , Sudhir Mehta 1 , Abhishek Agarwal 1 , Vishal Gupta 1 , Ashwin Mathur 1 , Amita Kashyap 4 , A S Dua 4 , Dilip Raj 4 , Kapil Gupta 2 , Jitendra Kumar Gupta 2 , Neeraj Verma 5 , Amit Tak 2 ,
CONTEXT: The outbreak and spread of severe acute respiratory syndrome coronavirus 2 has led to a global exigency of colossal and monstrous proportions in terms of public health and economic crisis. Till date, no pharmaceutical agent is known to manage in terms of prevention and treatment of coronavirus disease 2019 (COVID-19), the disease caused by a novel virus.
AIMS: The aim of the present work was to understand the underlying disease profile and dynamics that could provide relevant inputs and insight into pathophysiology and prevent further spread and evolve management strategies of COVID-19 patients from data-driven techniques.
SETTINGS AND DESIGN: A retrospective observational descriptive study was conducted on 29 COVID-19 patients admitted at a premier medical institution of North India in the months of February and March 2020.
METHODS: The patients were diagnosed with reverse transcription-polymerase chain reaction test. Demographic, clinical, and laboratory data were collected.
RESULTS: The mean age of population was 38.8 years with male preponderance, of which two patients were residents of Italy, and others hailed from semi-arid and Western sandy arid regions of Rajasthan (urban population). The major presenting symptom complex of said COVID-19 sample population included fever (48%), cough (31%), and shortness of breath (17%). Most of the patients (83%) had no comorbidity. No clinical correlation (r) could be appreciated between the duration of test positivity and age of afflicted COVID-19 patients (r = −0.0976).
CONCLUSIONS: The present evaluation of various facets of the ongoing global pandemic of COVID-19 is an attempt to portray early clinical and epidemiological parameters of the menace of COVID-19 patients admitted at SMS Medical College and Attached Hospitals, Jaipur.
中文翻译：
印度北部一家主要医疗机构对COVID-19大流行的初步临床流行病学描述。
背景：严重的急性呼吸系统综合症冠状病毒2的暴发和蔓延，导致在公共卫生和经济危机方面，全球存在着巨大而巨大的紧急情况。迄今为止，尚无药物可预防和治疗冠状病毒疾病2019（COVID-19），这是一种新型病毒引起的疾病。
目的：本研究的目的是了解潜在的疾病概况和动态，这些数据可以为病理生理学提供相关的投入和见解，并通过数据驱动技术阻止COVID-19患者的进一步传播和发展管理策略。
设置和设计：回顾性观察性描述性研究对2020年2月和2020年3月在印度北部一家主要医疗机构收治的29例COVID-19患者进行了研究。
方法：对患者进行了逆转录-聚合酶链反应测试。收集了人口统计，临床和实验室数据。
结果：人口平均年龄为38.8岁，男性占优势，其中两名患者是意大利居民，其他人则来自拉贾斯坦邦的半干旱和西部沙质干旱地区（城市人口）。所述COVID-19样本人群的主要症状复合体包括发烧（48％），咳嗽（31％）和呼吸急促（17％）。大多数患者（83％）没有合并症。无临床相关性（r可以在测试阳性的持续时间和患病的COVID-19患者的年龄之间比较（r = -0.0976）。
结论：目前对正在进行的全球COVID-19大流行的各个方面的评估，是试图描绘出斋浦尔SMS医学院和附属医院收治的COVID-19患者的早期临床和流行病学参数。
更新日期：2020-07-01
Annals of Thoracic Medicine ( IF 2.1 ) Pub Date : 2020-07-01 , DOI: 10.4103/atm.atm_182_20 Sudhir Bhandari 1 , Ajit Singh Shaktawat 1 , Raman Sharma 1 , Amitabh Dube 2 , Shivankan Kakkar 3 , S Banerjee 1 , Prakash Keshwani 1 , Shrikant Sharma 1 , Sunil Mahavar 1 , C L Nawal 1 , Sudhir Mehta 1 , Abhishek Agarwal 1 , Vishal Gupta 1 , Ashwin Mathur 1 , Amita Kashyap 4 , A S Dua 4 , Dilip Raj 4 , Kapil Gupta 2 , Jitendra Kumar Gupta 2 , Neeraj Verma 5 , Amit Tak 2 ,
Affiliation
CONTEXT: The outbreak and spread of severe acute respiratory syndrome coronavirus 2 has led to a global exigency of colossal and monstrous proportions in terms of public health and economic crisis. Till date, no pharmaceutical agent is known to manage in terms of prevention and treatment of coronavirus disease 2019 (COVID-19), the disease caused by a novel virus.
AIMS: The aim of the present work was to understand the underlying disease profile and dynamics that could provide relevant inputs and insight into pathophysiology and prevent further spread and evolve management strategies of COVID-19 patients from data-driven techniques.
SETTINGS AND DESIGN: A retrospective observational descriptive study was conducted on 29 COVID-19 patients admitted at a premier medical institution of North India in the months of February and March 2020.
METHODS: The patients were diagnosed with reverse transcription-polymerase chain reaction test. Demographic, clinical, and laboratory data were collected.
RESULTS: The mean age of population was 38.8 years with male preponderance, of which two patients were residents of Italy, and others hailed from semi-arid and Western sandy arid regions of Rajasthan (urban population). The major presenting symptom complex of said COVID-19 sample population included fever (48%), cough (31%), and shortness of breath (17%). Most of the patients (83%) had no comorbidity. No clinical correlation (r) could be appreciated between the duration of test positivity and age of afflicted COVID-19 patients (r = −0.0976).
CONCLUSIONS: The present evaluation of various facets of the ongoing global pandemic of COVID-19 is an attempt to portray early clinical and epidemiological parameters of the menace of COVID-19 patients admitted at SMS Medical College and Attached Hospitals, Jaipur.
中文翻译：
印度北部一家主要医疗机构对COVID-19大流行的初步临床流行病学描述。
背景：严重的急性呼吸系统综合症冠状病毒2的暴发和蔓延，导致在公共卫生和经济危机方面，全球存在着巨大而巨大的紧急情况。迄今为止，尚无药物可预防和治疗冠状病毒疾病2019（COVID-19），这是一种新型病毒引起的疾病。
目的：本研究的目的是了解潜在的疾病概况和动态，这些数据可以为病理生理学提供相关的投入和见解，并通过数据驱动技术阻止COVID-19患者的进一步传播和发展管理策略。
设置和设计：回顾性观察性描述性研究对2020年2月和2020年3月在印度北部一家主要医疗机构收治的29例COVID-19患者进行了研究。
方法：对患者进行了逆转录-聚合酶链反应测试。收集了人口统计，临床和实验室数据。
结果：人口平均年龄为38.8岁，男性占优势，其中两名患者是意大利居民，其他人则来自拉贾斯坦邦的半干旱和西部沙质干旱地区（城市人口）。所述COVID-19样本人群的主要症状复合体包括发烧（48％），咳嗽（31％）和呼吸急促（17％）。大多数患者（83％）没有合并症。无临床相关性（r可以在测试阳性的持续时间和患病的COVID-19患者的年龄之间比较（r = -0.0976）。
结论：目前对正在进行的全球COVID-19大流行的各个方面的评估，是试图描绘出斋浦尔SMS医学院和附属医院收治的COVID-19患者的早期临床和流行病学参数。
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