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Anti-interleukin-6 monoclonal antibody for cytokine storm in COVID-19.
Annals of Thoracic Medicine ( IF 2.1 ) Pub Date : 2020-07-01 , DOI: 10.4103/atm.atm_286_20
Steven Douedi 1 , Moiuz Chaudhri 1 , Jeffrey Miskoff 2, 3
Affiliation  


Novel coronavirus disease 2019 (COVID-19) is known to cause severe pneumonia and acute respiratory distress syndrome which may lead to death. Several treatments have been tested in the race to find a treatment regimen for this deadly viral infection. Tocilizumab, a recombinant humanized anti-interleukin-6 receptor monoclonal antibody, has been used and found to be beneficial in patients with COVID-19 and in cytokine storm. We present the case of a young, otherwise healthy male, presenting with COVID-19 and successfully treated in the intensive care unit with tocilizumab.


中文翻译:

抗白细胞介素6单克隆抗体,用于COVID-19中的细胞因子风暴。


已知新型冠状病毒病2019(COVID-19)会导致严重的肺炎和急性呼吸窘迫综合症,甚至可能导致死亡。为了寻找这种致命病毒感染的治疗方案,已经在竞赛中测试了几种治疗方法。重组人源化抗白介素6受体单克隆抗体Tocilizumab已被使用,发现对COVID-19患者和细胞因子风暴有益。我们介绍了一个年轻的,否则为健康的男性的案例,该患者出现了COVID-19,并在重症监护病房成功接受了tocilizumab的治疗。
更新日期:2020-07-01
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