Morphological and Transcriptional Changes in Human Bone Marrow During Natural Plasmodium vivax Malaria Infections.,The Journal of Infectious Diseases

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Morphological and Transcriptional Changes in Human Bone Marrow During Natural Plasmodium vivax Malaria Infections.
The Journal of Infectious Diseases ( IF 5.0 ) Pub Date : 2020-06-18 , DOI: 10.1093/infdis/jiaa177
Marcelo A M Brito _{1,

2} , Bàrbara Baro _{1,

3} , Tainá C Raiol ₄ , Alberto Ayllon-Hermida ₃ , Izabella P Safe ₁ , Katrien Deroost ₁ , Erick F G Figueiredo _{1,

2} , Allyson G Costa _{1,

2} , Maria Del P Armengol ₅ , Lauro Sumoy ₅ , Anne C G Almeida _{1,

2} , Bidossessi W Hounkpe ₆ , Erich V De Paula _{6,

7} , Cármen Fernandez-Becerra _{3,

5} , Wuelton M Monteiro _{1,

2} , Hernando A Del Portillo _{3,

5,

8} , Marcus V G Lacerda _{1,

2,

9}

Affiliation

The presence of Plasmodium vivax malaria parasites in the human bone marrow (BM) is still controversial. However, recent data from a clinical case and experimental infections in splenectomized nonhuman primates unequivocally demonstrated the presence of parasites in this tissue.

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