The growing population of peri-implant diseases (PIDs) has become a public obsession, mainly due to the lack of antibacterial ability and osteogenic promotion of titanium (Ti) implants. Herein, inspired by tremella, we reported zinc oxide (ZnO)@collagen type I (Col-I)-decorated Ti for PIDs treatments. Compared with pure Ti implants, ZnO@Col-I-decorated Ti could be activated by a safe visible yellow light and showed excellent broad-spectrum antibacterial properties. The proliferation and osteogenic gene expression of bone marrow mesenchymal stem cells (BMSCs) indicated that the triple osseointegration of implants was realized through (I) the remarkedly improved surface hydrophilicity of ZnO@Col-I-decorated Ti, (II) the function of Col-I, and (III) the excellent near-infrared (NIR)-induced photothermal performance of ZnO. Collectively, the proposed dual-light-defined ZnO@Col-I coating was a promising implant surface modification system to provide customized treatments for each PID patient.

中文翻译：

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银耳状ZnO @ Col-I装饰的钛表面具有双光定义的广谱抗菌和三重成骨特性。

种植体周围疾病（PID）人口的增长已成为公众的困扰，这主要是由于缺乏抗菌能力和钛（Ti）植入物的成骨促进。在这里，受银耳的启发，我们报道了氧化锌（ZnO）@胶原I型（Col-I）装饰的Ti用于PID的治疗。与纯钛植入物相比，ZnO @ Col-I装饰的钛可以被安全的可见黄光激活，并显示出出色的广谱抗菌性能。骨髓间充质干细胞（BMSCs）的增殖和成骨基因表达表明，植入物的三重骨整合是通过（I）显着改善的ZnO @ Col-I修饰的Ti的表面亲水性，（II）Col的功能实现的-I和（III）出色的近红外（NIR）诱导的ZnO光热性能。总的来说，