The recent article of Khan et al.¹ opens a new field of research in bipolar disorders and other psychiatric disorders, which can give clues for a better understanding of their pathophysiology. These authors provide an analysis of two large national datasets, highlighting the issue of air pollution as a risk factor for major psychiatric disorders. The authors show the influence of different environmental factors, including air pollution characteristics, on the general population prevalence of four psychiatric disorders (bipolar disorder, major depression, schizophrenia, and personality disorders taken as a whole) in Denmark and the USA. Their results show that poor air quality is associated with an elevated prevalence of bipolar disorders both in US and Denmark, and with elevated prevalence of schizophrenia, major depression and personality disorders also being associated with poor air quality in Denmark.

中文翻译：

---

空气污染和精神疾病：当前和未来的挑战。

Khan等人的最新文章。^1个开创了双相情感障碍和其他精神疾病的新研究领域，可以为更好地了解其病理生理学提供线索。这些作者对两个大型国家数据集进行了分析，强调了空气污染作为主要精神疾病的危险因素的问题。作者展示了不同的环境因素（包括空气污染特征）对丹麦和美国的四种精神疾病（双相情感障碍，重度抑郁症，精神分裂症和人格障碍整体）的总体人口患病率的影响。他们的结果表明，空气质量差与美国和丹麦的双相情感障碍患病率升高以及精神分裂症的患病率升高有关，