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Why behavioral neuroscience still needs diversity?: A curious case of a persistent need.
Neuroscience & Biobehavioral Reviews ( IF 7.5 ) Pub Date : 2020-06-18 , DOI: 10.1016/j.neubiorev.2020.06.021
Ajay S Mathuru 1 , Frédéric Libersat 2 , Ajai Vyas 3 , Serafino Teseo 3
Affiliation  

In the past few decades, a substantial portion of neuroscience research has moved from studies conducted across a spectrum of animals to reliance on a few species. While this undoubtedly promotes consistency, in-depth analysis, and a better claim to unraveling molecular mechanisms, investing heavily in a subset of species also restricts the type of questions that can be asked, and impacts the generalizability of findings. A conspicuous body of literature has long advocated the need to expand the diversity of animal systems used in neuroscience research. Part of this need is utilitarian with respect to translation, but the remaining is the knowledge that historically, a diverse set of species were instrumental in obtaining transformative understanding. We argue that diversifying matters also because the current approach limits the scope of what can be discovered. Technological advancements are already bridging several practical gaps separating these two worlds. What remains is a wholehearted embrace by the community that has benefitted from past history. We suggest the time for it is now.



中文翻译:

为什么行为神经科学仍然需要多样性?:一个持续存在的奇怪案例。

在过去的几十年中,神经科学研究的很大一部分已经从对多种动物进行的研究转向对少数物种的依赖。尽管这无疑会促进一致性,深入分析并更好地阐明分子机制,但在子物种的子集上大量投资也限制了可以提出的问题类型,并影响了研究结果的推广性。长期以来,大量的著名文献都提倡扩大神经科学研究中使用的动物系统的多样性。在翻译方面,这种需求的一部分是功利的,但剩下的是,从历史上看,各种各样的物种在获得转化理解方面起着重要作用。我们认为多元化也很重要,因为当前的方法限制了可发现事物的范围。技术进步已经弥合了分隔这两个世界的几个实际差距。剩下的就是从过去的历史中受益的社区的全心全意的拥抱。我们建议现在是时候了。

更新日期:2020-06-29
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