Crinum asiaticum L. (family: Amaryllidaceae) is a widely used medicinal plant species having great ethnomedicinal values. The present study aimed to evaluate in vitro antioxidant and antimicrobial potentials of the leaf extracts of C. asiaticum with their phenolics content. The total antioxidant assay, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, and ferric ion reducing antioxidant power (FRAP) assays of the leaf crude aqueous extract and the five successive extract fractions were analyzed to evaluate their antioxidant potential. The antimicrobial potential was investigated against two gram-negative and one gram-positive bacteria strain by the disc diffusion method. The aqueous fraction of C. asiaticum (CaAq) showed relatively higher antimicrobial potentials than the crude aqueous extract (CaLAE), in terms of zone of inhibition, indicating the fact that serial extraction procedure can more successfully concentrate the specific bioactive components. Along with CaAq and CaLAE, CaEA fraction (ethyl acetate extract fraction) also exhibits antimicrobial activities probably due to the presence of terpenoids, phenolics, and flavonoids. It might be concluded that antioxidants and antimicrobial agents are available in the leaves of C. asiaticum where water and ethyl acetate might be the effective solvent systems to extract antimicrobial and antioxidant agents respectively.

Crinum asiaticum L.（科：金眼科）是一种广泛使用的药用植物，具有极高的民族价值。本研究旨在评估含酚量的积雪草叶片提取物的体外抗氧化和抗菌潜力。分析了叶粗水提物和五个连续提取物馏分的总抗氧化剂测定，1,1-二苯基-2-吡啶并二肼（DPPH）自由基清除活性和三价铁离子还原抗氧化剂能力（FRAP）测定以评估其抗氧化剂潜在。通过圆盘扩散法研究了对两种革兰氏阴性和一种革兰氏阳性细菌菌株的抗菌潜力。积雪草的水部分就抑制区域而言，CaAq（CaAq）显示出比粗制水提取物（CaLAE）更高的抗菌潜力，表明连续提取程序可以更成功地浓缩特定生物活性成分。与CaAq和CaLAE一起，CaEA馏分（乙酸乙酯提取物馏分）也表现出抗菌活性，这可能是由于存在萜类化合物，酚类和黄酮类化合物。可以得出的结论是，积雪草的叶子中有抗氧化剂和抗微生物剂，其中水和乙酸乙酯可能是分别提取抗微生物剂和抗氧化剂的有效溶剂系统。