Flow chemistry has progressed considerably in recent years from basic laboratory techniques in organic synthetic chemistry to complex, multistep processes in practice. In this perspective review, missing links that represent opportunities for chemists and chemical engineers are examined. New avenues in reaction chemistry are expanding the molecular toolbox, which includes green and cascade catalysis. Next generation engineering concepts such as machine intelligence and sustainable manufacturing have become a reality, opening the door to interdisciplinary work unlike before. Emerging trends that have the potential to start new fields of research and technological advancements are also highlighted. Flow chemistry is rewriting the traditional chemistry laboratory and our scientific discovery infrastructure. Enormous opportunities remain for groundbreaking science and engineering from this exciting field that demands a well-trained workforce for its industrial practice. The groundwork is being laid now for industries of the future such as continuous-flow biologics, biopharmaceuticals, and implementation of the nanomaterials revolution.

近年来，从有机合成化学的基本实验室技术到实践中复杂的多步工艺，流化学已经取得了长足的进步。在此观点回顾中，检查了代表化学家和化学工程师机会的缺失链接。反应化学的新途径正在扩展分子工具箱，其中包括绿色催化和级联催化。诸如机器智能和可持续制造之类的下一代工程概念已经成为现实，这为跨学科工作打开了大门。还着重指出了可能启动新的研究和技术进步领域的新兴趋势。流化学正在改写传统化学实验室和我们的科学发现基础设施。在这个令人兴奋的领域中，具有开创性的科学和工程领域仍然存在巨大的机会，这需要训练有素的劳动力来从事其工业实践。现在正在为未来的行业奠定基础，例如连续流生物制剂，生物制药以及纳米材料革命的实施。