The current article presents a brief historical perspective on Professor John D Biggers, PhD, DSc. who died on 7 April, 2018. His interests covered reproductive physiology, embryo culture, cryobiology, sperm preservation, statistics and experimental design, and the history and ethics of human reproductive biology. Emphasis is placed on John Biggers’ approach to the development of media for the culture of mammalian preimplantation embryos and to correct several minor misconceptions that have arisen in recent years regarding some of his studies. Much can be learned from his detailed approach to scientific investigation and experimental design. His scientific accomplishments and seminal contributions are important, but the tapestry of his life and legacy continue to be woven through the many students, fellows, and collaborators with whom he worked with over many years. The present article builds on a previous conversation that Michael Summers and Catherine Racowsky had with John Biggers that was published in 2008 [1].

当前文章简要介绍了 John D Biggers 教授的历史观点，博士，理学硕士。他于 2018 年 4 月 7 日去世。他的兴趣涵盖生殖生理学、胚胎培养、冷冻生物学、精子保存、统计学和实验设计，以及人类生殖生物学的历史和伦理。重点放在约翰·比格斯 (John Biggers) 开发用于哺乳动物植入前胚胎培养的培养基的方法上，并纠正近年来在他的一些研究中出现的几个小误解。从他详细的科学调查和实验设计方法中可以学到很多东西。他的科学成就和开创性贡献很重要，但他的生平和遗产的挂毯继续通过许多学生、研究员、以及与他合作多年的合作者。本文基于 Michael Summers 和 Catherine Racowsky 与 John Biggers 的先前对话，该对话于 2008 年发表 [1]。