当前位置：
X-MOL 学术
›
Org. Biomol. Chem.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Copper-catalyzed 1,3-aminothiocyanation of arylcyclopropanes.
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2020-06-17 , DOI: 10.1039/d0ob01060j Xiaomin Wang 1 , Lihong Wang 1 , Shengbiao Yang 1 , Linli Zhang 1 , Yan Li 1 , Qian Zhang 2
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2020-06-17 , DOI: 10.1039/d0ob01060j Xiaomin Wang 1 , Lihong Wang 1 , Shengbiao Yang 1 , Linli Zhang 1 , Yan Li 1 , Qian Zhang 2
Affiliation
|
A copper-catalyzed 1,3-aminothiocyanation of arylcyclopropanes with N-fluorobenzenesulfonimide (NFSI) and trimethylsilyl isothiocyanate (TMSNCS) has been developed for the first time, efficiently synthesizing a series of γ-aminothiocyanate derivatives in moderate to excellent yields from readily available substrates under mild conditions. The practicability of the reaction was demonstrated by gram-scale preparation. Furthermore, the easily prepared γ-aminothiocyanate derivatives were verified to be versatile building blocks.
中文翻译：
铜催化的芳基环丙烷的1,3-氨基硫氰化。
首次开发了用N-氟苯磺酰亚胺（NFSI）和三甲基甲硅烷基异硫氰酸酯（TMSNCS）进行的铜催化芳基环丙烷的1,3-氨基硫氰化反应，可有效地从容易获得的底物中高效合成一系列γ-氨基硫氰酸酯衍生物在温和的条件下。通过克规模的制备证明了该反应的实用性。此外，已证实容易制备的γ-氨基硫氰酸酯衍生物是通用的构建基块。
更新日期：2020-07-08
中文翻译：
铜催化的芳基环丙烷的1,3-氨基硫氰化。
首次开发了用N-氟苯磺酰亚胺（NFSI）和三甲基甲硅烷基异硫氰酸酯（TMSNCS）进行的铜催化芳基环丙烷的1,3-氨基硫氰化反应，可有效地从容易获得的底物中高效合成一系列γ-氨基硫氰酸酯衍生物在温和的条件下。通过克规模的制备证明了该反应的实用性。此外，已证实容易制备的γ-氨基硫氰酸酯衍生物是通用的构建基块。
京公网安备 11010802027423号