Cytokine storm in COVID-19 is characterized by an excessive inflammatory response to SARS-CoV-2 that is caused by a dysregulated immune system of the host. We are proposing a new hypothesis that SARS-CoV-2 mediated inflammation of nucleus tractus solitarius (NTS) may be responsible for the cytokine storm in COVID 19. The inflamed NTS may result in a dysregulated cholinergic anti-inflammatory pathway and hypothalamic–pituitary–adrenal axis.

中文翻译：

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COVID19中的细胞因子风暴：神经假说。

COVID-19中的细胞因子风暴的特征是对SARS-CoV-2的过度炎症反应，这是由宿主免疫系统失调引起的。我们提出了一个新的假设，即SARS-CoV-2介导的孤索核（NTS）炎症可能是导致COVID 19中细胞因子风暴的原因。发炎的NTS可能导致胆碱能抗炎途径和下丘脑-垂体-腺体失调。肾上腺轴。