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A Metabolic Perspective and Opportunities in Pharmacologically Important Safflower.
Metabolites ( IF 3.4 ) Pub Date : 2020-06-17 , DOI: 10.3390/metabo10060253
Vimalraj Mani 1 , Seon-Kyeong Lee 1 , Yunsoo Yeo 1 , Bum-Soo Hahn 2
Affiliation  

Safflower (Carthamus tinctorius L.) has long been grown as a crop due to its commercial utility as oil, animal feed, and pharmacologically significant secondary metabolites. The integration of omics approaches, including genomics, transcriptomics, metabolomics, and proteomics datasets, has provided more comprehensive knowledge of the chemical composition of crop plants for multiple applications. Knowledge of a metabolome of plant is crucial to optimize the evolution of crop traits, improve crop yields and quality, and ensure nutritional and health factors that provide the opportunity to produce functional food or feedstuffs. Safflower contains numerous chemical components that possess many pharmacological activities including central nervous, cardiac, vascular, anticoagulant, reproductive, gastrointestinal, antioxidant, hypolipidemic, and metabolic activities, providing many other human health benefits. In addition to classical metabolite studies, this review focuses on several metabolite-based working techniques and updates to provide a summary of the current medical applications of safflower.

中文翻译:

药理学上重要的红花的新陈代谢前景和机遇。

红花(红花)L.)长期作为农作物生长,由于其商业用途为油,动物饲料和具有药理学意义的次生代谢产物。包括基因组学,转录组学,代谢组学和蛋白质组学数据集在内的组学方法的集成,为多种应用提供了关于作物化学成分的更全面的知识。了解植物的代谢组对于优化农作物性状的进化,提高农作物的产量和质量以及确保营养和健康因素(提供生产功能性食品或饲料的机会)至关重要。红花含有许多化学成分,这些化学成分具有许多药理活性,包括中枢神经,心脏,血管,抗凝剂,生殖,胃肠道,抗氧化剂,降血脂和代谢活性,提供许多其他人类健康益处。除了经典的代谢物研究之外,本文还将重点介绍几种基于代谢物的工作技术和更新,以概述红花的当前医学应用。
更新日期:2020-06-17
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