Commercial pulse oximeters are used clinically to measure heart rate and blood oxygen saturation and traditionally made from rigid materials. However, these devices are unsuitable for continuous monitoring due to poor fit and mechanical mismatch. Soft materials that match the elastic properties of biological tissue provide improved comfort and signal‐to‐noise but typically require molding to manufacture, limiting the speed and ease of customizing for patient‐specific anatomy. Here, freeform reversible embedding (FRE) 3D printing is used to create polydimethylsiloxane (PDMS) elastomer cuffs for use on the hand and foot. FRE enables printing liquid PDMS prepolymer in 3D geometries within a sacrificial hydrogel bath that provides support during cure. This serves as proof‐of‐concept for fabricating patient‐specific pulse oximeters with pressure sensing, termed P³‐wearable. A sizing analysis establishes dimensional accuracy of FRE‐printed PDMS compared to anatomical computer‐aided design models. The P³‐wearable successfully outputs photoplethysmography (PPG) and pressure amplitude signals wirelessly to a tablet in real time and the PPG is used to calculate heart rate, blood oxygen content, and activity state. The results establish that FRE printing of PDMS can be used to fabricate patient‐specific wearable devices and measure heart rate and blood oxygenation on par with commercial devices.

中文翻译：

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用于患者专用的可穿戴式脉搏血氧仪的3D打印有机硅弹性体。

商业脉搏血氧仪在临床上用于测量心率和血氧饱和度，传统上是由刚性材料制成的。但是，由于装配不良和机械失配，这些设备不适合连续监控。与生物组织的弹性特性相匹配的软材料可提供更高的舒适度和信噪比，但通常需要模制才能制造，从而限制了针对患者特定解剖结构进行定制的速度和简便性。在这里，自由形式可逆嵌入（FRE）3D打印用于创建聚二甲基硅氧烷（PDMS）弹性袖带，用于手和脚。FRE可以在牺牲性水凝胶浴中以3D几何形状打印液态PDMS预聚物，在固化过程中提供支撑。³耐磨。尺寸分析可以确定FRE打印的PDMS与解剖学计算机辅助设计模型相比的尺寸精度。可穿戴式P ³成功地将光体积描记法（PPG）和压力幅度信号无线地实时输出到平板电脑，并且PPG用于计算心率，血氧含量和活动状态。结果表明，PDMS的FRE打印可用于制造针对患者的可穿戴设备，并与商用设备相媲美地测量心率和血液氧合。