Ferrocene is of great significance in the fields of organic synthesis, materials science, and biomedical research. Of particular importance is the fact that ferrocenes with planar chirality have proven to be privileged ligands or catalysts for asymmetric catalysis. Therefore, developing highly efficient methods to introduce planar chirality on the backbone of ferrocene is desirable. This short review highlights recent advances towards enantioselective C–H bond functionalization of ferrocenes. Enantioselective synthesis of planar chiral ferrocenes via Pd-, Ir-, Rh-, Au-, Pt-, and Ni-catalyzed C–H bond functionalization is described. The achievements in asymmetric C–H bond functionalization provide a rich platform for the design and synthesis of planar chiral ferrocenes.

二茂铁在有机合成，材料科学和生物医学研究领域中具有重要意义。特别重要的事实是，具有平面手性的二茂铁已被证明是不对称催化的优先配体或催化剂。因此，需要开发在二茂铁的骨架上引入平面手性的高效方法。这篇简短的评论重点介绍了二茂铁对映选择性C–H键功能化的最新进展。描述了通过Pd-，Ir-，Rh-，Au-，Pt-和Ni催化的C–H键官能化的平面手性二茂铁的对映选择性合成。不对称CH键的功能化成就为平面手性二茂铁的设计和合成提供了一个丰富的平台。