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Efficient and multi-function compatible click-reaction of organosilanes
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-06-17 , DOI: 10.1016/j.tetlet.2020.152145
Robert Winkler , Stéphane Pellet-Rostaing , Guilhem Arrachart

The synthesis of organotriethoxysilanes by click chemistry was studied using the recyclable, multidentate catalyst [Cu(C18tren)]Br. For the evaluation, alkyne precursors containing some of the more common organic functions were reacted with a triethoxy silyl group containing azide. The procedure allowed the isolation of the desired products in high yields and high purity. Especially remarkable is the facility of the catalyst removal by simple filtration and evaporation. The catalyst is concluded to be ideal for the synthesis of moisture sensitive organotriethoxysilanes.



中文翻译:

高效且多功能的有机硅烷点击反应

使用可循环的多齿催化剂[Cu(C 18 tren)] Br ,研究了通过点击化学合成有机三乙氧基硅烷的方法。为了进行评估,使含有一些更常见的有机官能团的炔烃前体与含有三乙氧基甲硅烷基的叠氮化物反应。该程序允许以高收率和高纯度分离所需产物。通过简单的过滤和蒸发除去催化剂的设施尤其引人注目。结论是该催化剂是合成湿敏性有机三乙氧基硅烷的理想选择。

更新日期:2020-07-05
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