The current requirement for expensive laboratory equipment and highly trained personnel highlights the critical need for simple, low cost technologies capable of point-of-care (POC) clinical detection, especially in resource-limited regions. In this report, we propose an innovative, ultra low-cost, plastic-based blood diagnostic platform for POC detection that requires only a minute volume (< 3.0 μL) of human whole blood. We integrated a spray-coated superhydrophilic plastic substrate with hydrophobic adhesive tapes, which triggers plasma isolation upon a finger-powered asymmetric capillary force. We simply quantified the biosensing capability of the developed blood diagnostic chip using a finger-powered, capillary-driven colorimetric assay.

当前对昂贵的实验室设备和训练有素的人员的需求突显了对简单，低成本技术的迫切需求，这些技术能够进行即时医疗（POC）临床检测，尤其是在资源有限的地区。在本报告中，我们提出了一种创新的，基于塑料的超低成本血液诊断平台，可用于POC检测，该平台仅需一分钟（<3.0μL）的人类全血。我们将喷涂的超亲水性塑料基材与疏水性胶带整合在一起，在手指提供动力的不对称毛细作用力的作用下，可触发血浆分离。我们使用手指驱动的毛细管驱动比色法简单地量化了开发的血液诊断芯片的生物传感能力。