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Radiolabeled liposomes and lipoproteins as lipidic nanoparticles for imaging and therapy.
Chemistry and Physics of Lipids ( IF 3.4 ) Pub Date : 2020-06-17 , DOI: 10.1016/j.chemphyslip.2020.104934 Liliana Aranda-Lara 1 , Enrique Morales-Avila 2 , Myrna A Luna-Gutiérrez 3 , Eunice Olivé-Alvarez 4 , Keila Isaac-Olivé 1
中文翻译：
放射性标记的脂质体和脂蛋白为脂质纳米颗粒，用于成像和治疗。
更新日期：2020-06-23
Chemistry and Physics of Lipids ( IF 3.4 ) Pub Date : 2020-06-17 , DOI: 10.1016/j.chemphyslip.2020.104934 Liliana Aranda-Lara 1 , Enrique Morales-Avila 2 , Myrna A Luna-Gutiérrez 3 , Eunice Olivé-Alvarez 4 , Keila Isaac-Olivé 1
Affiliation
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Radiolabeled lipidic nanoparticles, particularly liposomes and lipoproteins, are of great interest as agents for imaging and therapy, due not only to their peculiar physicochemical and biological properties, but also to their great versatility and the ability to manipulate them to obtain the desired properties. This review provides an overview of radionuclide labeling strategies for preparing diagnostic and therapeutic nanoparticles based on liposomes and lipoproteins that have been developed to date, as well as the main quality control methods and in vivo applications.
中文翻译：
放射性标记的脂质体和脂蛋白为脂质纳米颗粒，用于成像和治疗。
放射性标记的脂质纳米颗粒，特别是脂质体和脂蛋白，作为成像和治疗剂备受关注，这不仅是由于其独特的理化和生物学特性，而且还因为它们的多功能性和操纵它们以获得所需特性的能力。这篇综述概述了放射性核素标记策略的制备方法，该策略用于基于迄今已开发的脂质体和脂蛋白制备诊断和治疗性纳米颗粒，以及主要的质量控制方法和体内应用。
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