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Palladium-Catalyzed Intermolecular Heck-Type Dearomative [4 + 2] Annulation of 2H-Isoindole Derivatives with Internal Alkynes.
Organic Letters ( IF 5.2 ) Pub Date : 2020-06-15 , DOI: 10.1021/acs.orglett.0c01643
Tengfei Yao 1 , Fang Zhang 1 , Junliang Zhang 2 , Lu Liu 1, 3
Affiliation  

Here, an interesting palladium-catalyzed intermolecular Heck-type dearomative [4 + 2] annulation of 2H-isoindole derivatives with internal alkynes has been developed, affording diverse polycyclic pyrrolidine scaffolds in good yield. This reaction is a useful method for the transformation of 2H-isoindole.

中文翻译:

钯催化的分子间Heck型脱芳香剂[4 + 2]与2H-异吲哚衍生物与内部炔烃的环化。

在这里,开发了一种有趣的钯催化的2 H-异吲哚衍生物与内部炔烃的Heck型分子间Heck型脱芳香剂[4 + 2]环化反应,以收率提供了多种多环吡咯烷骨架。该反应是转化2 H-异吲哚的有用方法。
更新日期:2020-07-02
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