ABSTRACT An efficient one-pot four-component condensation of naphthols with formaldehyde, carbon disulfide and secondary amines in water is described for the synthesis of 1-(dithiocarbamatomethyl)-2-naphthols and 2-(dithiocarbamatomethyl)-1-naphthols. By using naphthalene-2,3-diol in this protocol, the corresponding bis(dithiocarbamates) were obtained in high yields via a one-pot pseudo seven-component reaction. The reaction is characterized by a wide substrate scope, high efficiency, green solvent, catalyst-free conditions and straightforward isolation protocol. Employing this newly developed multicomponent reaction enabled the synthesis of 26 dithiocarbamates. GRAPHICAL ABSTRACT

中文翻译：

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一种方便的四组分反应，用于从水中的萘酚合成二硫代氨基甲酸酯

摘要描述了萘酚与甲醛、二硫化碳和仲胺在水中的有效一锅四组分缩合反应，用于合成 1-(二硫代氨基甲酸甲酯)-2-萘酚和 2-(二硫代氨基甲酸甲酯)-1-萘酚。通过在该协议中使用萘-2,3-二醇，通过一锅伪七组分反应以高产率获得了相应的双（二硫代氨基甲酸酯）。该反应的特点是底物范围广、效率高、绿色溶剂、无催化剂条件和简单的分离方案。采用这种新开发的多组分反应可以合成 26 种二硫代氨基甲酸酯。图形概要