Optically activated and interrogated plasmonic hydrogels for applications in wound healing.,Journal of Biophotonics

当前位置： X-MOL 学术 › J. Biophotonics › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Optically activated and interrogated plasmonic hydrogels for applications in wound healing.
Journal of Biophotonics ( IF 2.0 ) Pub Date : 2020-06-25 , DOI: 10.1002/jbio.202000135
Alessio Milanesi _{1,

2} , Giada Magni ₁ , Sonia Centi ₁ , Gioacchino Schifino ₃ , Annalisa Aluigi ₃ , Boris N Khlebtsov ₄ , Lucia Cavigli ₁ , Andrea Barucci ₁ , Nikolai G Khlebtsov _{4,

5} , Fulvio Ratto ₁ , Francesca Rossi ₁ , Roberto Pini ₁

Affiliation

We disclose the use of hybrid materials featuring Au/Ag core/shell nanorods in porous chitosan/polyvinyl alcohol scaffolds for applications in tissue engineering and wound healing. The combination of Au and Ag in a single construct provides synergistic opportunities for optical activation of functions as near infrared laser tissue bonding, and remote interrogation to return parameters of prognostic relevance in wound healing monitoring. In particular, the bimetallic component ensures optical tunability, enhanced shelf life and photothermal stability, serves as a reservoir of germicidal silver cations, and changes in near‐infrared and visible color according to the environmental level of oxidative stress. At the same time, the polymeric blend is ideal to bind connective tissue upon photothermal activation, and to support fabrication processes that provide high porosity, such as electrospinning, thus putting all the premises for cellular repopulation and antimicrobial protection.

中文翻译：

光学活化和审定的等离激水凝胶，用于伤口愈合。

我们公开了在多孔壳聚糖/聚乙烯醇支架中使用以金/银核/壳纳米棒为特征的混合材料，用于组织工程和伤口愈合。Au和Ag的组合在单个构建体中为光学激活功能提供了协同机会，这些功能包括近红外激光组织键合以及远程询问以返回伤口愈合监测中预后相关参数。特别是，双金属成分可确保光学可调性，延长的货架期和光热稳定性，可作为杀菌银阳离子的储存库，并根据环境中的氧化应激水平而改变近红外和可见颜色。同时，聚合物共混物非常适合在光热激活后结合结缔组织，

更新日期：2020-06-25

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11