A biobank is an organized collection of biological human material and its associated information stored for research according to regulations under institutional responsibility, without commercial purposes, being a mandatory and strategical activity for research, regenerative medicine, and innovation. Stem cells have largely been employed in research and frequently stored in biobanks, which have been used as an essential source of biological materials. Stem cells of human exfoliated deciduous teeth (SHED) are stem cells which have a high multipotency and can be easily obtained. Besides, this extremely accessible tissue has advantages with respect to storage, as the SHED obtained in childhood can be used in later life, which implies the necessity for the creation and regulation of biobanks. The proper planning for the creation of a biobank includes knowledge of the material types to be stored, requirements regarding handling and storage conditions, storage time, and room for the number of samples. Thus, this study aimed to establish an overview of the development of a SHED biobank. Ethical and legal standardization, current applications, specific orientations, and challenges for the implementation of a SHED biobank were discussed. Through this overview, we hope to encourage further studies to use SHED biobanks.

中文翻译：

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人类脱落乳牙干细胞生物库：巴西应用和发展概况

生物库是有组织的人体生物材料及其相关信息的集合，根据机构责任下的规定存储用于研究，没有商业目的，是研究、再生医学和创新的强制性和战略性活动。干细胞已大量用于研究并经常储存在生物库中，生物库已被用作生物材料的重要来源。人类脱落乳牙（SHED）的干细胞是具有高多能性且容易获得的干细胞。此外，这种极其易接近的组织在储存方面具有优势，因为童年时期获得的 SHED 可以在以后的生活中使用，这意味着创建和监管生物库的必要性。创建生物样本库的正确计划包括了解要存储的材料类型、处理和存储条件的要求、存储时间以及样本数量的空间。因此，本研究旨在概述 SHED 生物库的发展。讨论了实施 SHED 生物库的道德和法律标准化、当前应用、具体方向和挑战。通过这个概述，我们希望鼓励进一步研究使用 SHED 生物库。并讨论了实施 SHED 生物库的挑战。通过这个概述，我们希望鼓励进一步研究使用 SHED 生物库。并讨论了实施 SHED 生物库的挑战。通过这个概述，我们希望鼓励进一步研究使用 SHED 生物库。