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Photocatalytic trifluoromethoxylation of arenes and heteroarenes in continuous-flow.
Beilstein Journal of Organic Chemistry ( IF 2.2 ) Pub Date : 2020-06-15 , DOI: 10.3762/bjoc.16.111
Alexander V Nyuchev 1 , Ting Wan 1 , Borja Cendón 1, 2 , Carlo Sambiagio 1 , Job J C Struijs 1 , Michelle Ho 1 , Moisés Gulías 2 , Ying Wang 3 , Timothy Noël 1
Affiliation  

The first example of photocatalytic trifluoromethoxylation of arenes and heteroarenes under continuous-flow conditions is described. Application of continuous-flow microreactor technology allowed to reduce the residence time up to 16 times in comparison to the batch procedure, while achieving similar or higher yields. In addition, the use of inorganic bases was demonstrated to increase the reaction yield under batch conditions.

中文翻译:

连续流中芳烃和杂芳烃的光催化三氟甲氧基化。

描述了在连续流动条件下芳烃和杂芳烃的光催化三氟甲氧基化的第一个实例。与分批过程相比,连续流微反应器技术的应用使停留时间减少了多达16倍,同时实现了相似或更高的产量。另外,已证明在分批条件下使用无机碱可提高反应产率。
更新日期:2020-06-15
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