Contraceptive hormones are systemically active, potent, and likely to invoke biological responses other than known fertility regulation impacts. We hypothesized that initiation of depot medroxyprogesterone acetate (DMPA) would increase genital HIV‐target‐cells and soluble immune mediators compared with baseline and initiation of other contraceptive methods.

中文翻译：

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Zim CHIC：与开始和使用避孕药相关的女性生殖道免疫变化的队列研究。

避孕激素具有全身活性、效力，并且可能引发已知的生育调节影响以外的生物反应。我们假设，与基线和其他避孕方法的启动相比，长效醋酸甲羟孕酮 (DMPA) 的启动会增加生殖器 HIV 靶细胞和可溶性免疫介质。