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Malt and beer-related by-products as potential antioxidant skin-lightening agents for cosmetics
Sustainable Chemistry and Pharmacy ( IF 5.5 ) Pub Date : 2020-06-15 , DOI: 10.1016/j.scp.2020.100282
Martin Almendinger , Sascha Rohn , Daniel Pleissner

Malt and beer-related by-products, namely caramalt, aromatic malt, roasted malt, malt sprouts, dark beer spent grains, and wheat beer spent grains were extracted with water under moderate conditions to exploit the potential as sources of bioactive compounds. After characterizing the extracts in terms of carbohydrate, amino acid, and phenolic contents and composition, their antioxidant potential was assessed in vitro using keratinocyte cell cultures. Malt sprouts provided highest yields of glucose (50.1 mg g-1) and fructose (38.4 mg g-1), while the other materials gave up to 13.5 mg g-1. Furthermore, malt sprouts gave a total amino acid content of 57.6 mg g-1. Extracts of darker malts such as caramalt and roasted malt exhibited the highest yields of phenolic compounds of about 12.9 mg gallic acid equivalents (GAE) g-1 and extracts from spent grains had the lowest total yield with 5.1 and 1.8 mg GAE g-1 (dark beer and wheat beer spent grains), respectively. Phenolic compounds in caramalt extract inhibited the tyrosinase activity by 78% and 87%, when applying extract concentrations of 0.5% and 1%, respectively. Dark malt, roasted malt as well as the malt sprouts extracts achieved similar effects of 86% and 80% inhibition, when using a 1% extract. In contrast, extracts of spent grains showed low inhibitory effects. This study indicates the potential of malt and beer-related by-products as biological sources of ingredients for cosmeceutical products, for instance, in skin whitening.



中文翻译:

麦芽和啤酒相关的副产品可作为化妆品的潜在抗氧化剂亮肤剂

与麦芽和啤酒有关的副产品,即卡拉麦芽,芳香麦芽,烤麦芽,麦芽,黑啤酒废谷物和小麦啤酒废谷物在适当条件下用水提取,以挖掘其作为生物活性化合物来源的潜力。在根据碳水化合物,氨基酸,酚含量和组成对提取物进行表征后,使用角质形成细胞培养物在体外评估其抗氧化能力。麦芽可以提供最高的葡萄糖(50.1 mg g -1)和果糖(38.4 mg g -1)的产量,而其他材料的最高产量为13.5 mg g -1。此外,麦芽芽的总氨基酸含量为57.6 mg g -1。深色麦芽的提取物(如卡拉麦尔和烤麦芽)的酚类化合物产量最高,约为12.9 mg没食子酸当量(GAE)g -1,而废谷粒的提取物总产量最低,分别为5.1和1.8 mg GAE g -1(黑啤酒和小麦啤酒用过的谷物)。当分别以0.5%和1%的浓度提取提取物时,caramalt提取物中的酚类化合物可抑制酪氨酸酶活性78%和87%。当使用1%的提取物时,深色麦芽,烤的麦芽和麦芽芽提取物也达到了86%和80%的抑制效果。相反,废谷物的提取物显示出低抑制作用。这项研究表明,与麦芽和啤酒有关的副产品作为药用化妆品成分生物来源的潜力,例如在皮肤增白中。

更新日期:2020-06-15
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