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Liquid-liquid chromatography in enantioseparations.
Journal of Chromatography A ( IF 3.8 ) Pub Date : 2020-06-14 , DOI: 10.1016/j.chroma.2020.461345
Shengqiang Tong 1
Affiliation  

Modern liquid-liquid chromatography mainly refers to the following two kinds of chromatographic apparatuses: countercurrent chromatography based on hydrodynamic equilibrium systems and centrifugal partition chromatography based on hydrostatic equilibrium systems. In this paper, the recent advancements in enantioseparations by liquid-liquid chromatography, including the separation mechanism, chiral selector, two-phase solvent system, methods to improve the peak resolution and recent applications, are reviewed. The future outlook for liquid-liquid chromatography in enantioseparations is also proposed.



中文翻译:

对映体分离中的液-液色谱。

现代液-液相色谱法主要指以下两种色谱仪器:基于流体动力学平衡系统的逆流色谱法和基于流体静力学系统的离心分配色谱法。本文综述了液相色谱法对映体拆分的最新进展,包括分离机理,手性选择剂,两相溶剂体系,提高峰分离度的方法和最新应用。还提出了对映体分离中液-液色谱的未来展望。

更新日期:2020-06-23
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