Epilepsy occurs in nearly all patients with tuberous sclerosis and is often refractory to medical treatment. The definition of surgical candidacy in these patients has broadened in recent years due to philosophical and technological advances. The goals of surgery have shifted to focusing on quality of life and maximizing neurodevelopmental potential in patients unable to obtain seizure freedom. Novel diagnostic, ablative, and neuromodulatory techniques have been developed that may help patients that were previously considered inoperable to have an improved quality of life. In the coming years, it is expected that these techniques will be further refined and lead to an improvement of neurological prognosis in patients with tuberous sclerosis.

几乎所有患有结节性硬化症的患者都会发生癫痫病，并且通常难以接受药物治疗。由于哲学和技术的进步，近年来对这些患者进行手术候选资格的定义已经扩大。手术的目标已转移到关注生活质量和最大程度提高无法获得癫痫发作的患者的神经发育潜能。已经开发了新颖的诊断，消融和神经调节技术，这些技术可以帮助以前被认为无法手术的患者改善生活质量。在未来的几年中，预计这些技术将得到进一步完善，并导致结节性硬化症患者的神经系统预后得到改善。