Optical micro/nanofibre embedded soft film enables multifunctional flow sensing in microfluidic chips.,Lab on a Chip

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Optical micro/nanofibre embedded soft film enables multifunctional flow sensing in microfluidic chips.
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-06-13 , DOI: 10.1039/d0lc00178c
Zhang Zhang ₁ , Jing Pan , Yao Tang , Yue Xu , Lei Zhang , Yuan Gong , Limin Tong

Affiliation

Microfluidic chips have been proven to be a powerful technical platform for chemical synthesis, biomedical research, and optofluidic devices. Here, we report a smart microfluidic chip (SMC) with multiple functionality to sense the status or incidents occurring on chip. The SMC is enabled by a soft, flexible and attachable film embedded with optical micro/nanofibres (MNFs), which is highly compatible with microfluidic chips fabricated by lithography. Based on the transition from guided modes to radiation modes of the MNFs, simultaneous flow rate detection in multiple channels is demonstrated on a SMC with high sensitivity. The MNF-enabled SMC is also capable of monitoring the transportation and morphology of microfluidic droplets with fast response. In addition, real-time counting of the magnetic droplets is performed to verify the SMC's anti-electromagnetic interference ability. This SMC is unique and may play an important role in microreactors, droplet microfluidics and optofluidic sensors.

中文翻译：

光学微/纳米纤维嵌入的软膜可实现微流控芯片中的多功能流量传感。

微流体芯片已被证明是化学合成，生物医学研究和光流体设备的强大技术平台。在这里，我们报告一种具有多种功能的智能微流控芯片（SMC），以检测芯片上的状态或事件。SMC通过嵌入有光学微/纳米纤维（MNF）的柔软，灵活且可附着的薄膜实现，该薄膜与通过光刻技术制造的微流控芯片高度兼容。基于从MNFs的引导模式到辐射模式的转变，在具有高灵敏度的SMC上演示了多个通道中的同时流速检测。支持MNF的SMC还能够以快速响应来监视微流液滴的运输和形态。另外，执行磁滴的实时计数以验证SMC' 的抗电磁干扰能力。该SMC是独特的，并且可能在微反应器，液滴微流控和光电传感器中发挥重要作用。

更新日期：2020-07-14

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