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Building Bridges from Genome to Phenome: Molecules, Methods and Models—An Introduction to the Symposium
Integrative and Comparative Biology ( IF 2.2 ) Pub Date : 2020-06-13 , DOI: 10.1093/icb/icaa073
Karen G Burnett 1 , David S Durica 2 , Donald L Mykles 3 , Jonathon H Stillman 4
Affiliation  

How stable genotypes interact with their environment to generate phenotypic variation that can be acted upon by evolutionary and ecological forces is a central focus of research across many scientific disciplines represented within SICB. The Building Bridges Symposium brought together scientists using a variety of organisms, methods, and levels of biological organization to study the emergent properties of genomes. Workshops associated with the Symposium aimed to identify the leading edges and major barriers to research in this field, and to recommend future directions that might accelerate the pace of progress. The papers included in this Symposium volume draw attention to the strength of using comparative approaches in non-model organisms to study the many aspects of genotype–environment interaction that drive phenotype variation. These contributions and the concluding white paper also illustrate the need for novel conceptual frameworks that can bridge and accommodate data and conclusions from the broad range of study systems employed by comparative and integrative biologists to address genome-to-phenome questions.

中文翻译:

建立从基因组到现象学的桥梁:分子,方法和模型—研讨会简介

稳定的基因型如何与其环境相互作用以产生表型变异,而进化和生态力量可以对表型变异起作用,这是SICB代表的许多科学学科研究的重点。建筑桥梁研讨会汇集了使用各种生物体,方法和生物组织水平的科学家,以研究基因组的新兴特性。与研讨会相关的研讨会旨在确定该领域研究的领先优势和主要障碍,并建议可能会加快进展速度的未来方向。研讨会论文集中的论文提请人们注意在非模式生物中使用比较方法研究驱动表型变异的基因型-环境相互作用的许多方面的优势。
更新日期:2020-06-13
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