Sequence logos give a fast and concise display in visualizing consensus sequence. Protein exhibits greater complexity and diversity than DNA, which usually affects the graphical representation of the logo. Reduced amino acids perform powerful ability for simplifying complexity of sequence alignment, which motivated us to establish RaacLogo. As a new sequence logo generator by using reduced amino acid alphabets, RaacLogo can easily generate many different simplified logos tailored to users by selecting various reduced amino acid alphabets that consisted of more than 40 clustering algorithms. This current web server provides 74 types of reduced amino acid alphabet, which were manually extracted to generate 673 reduced amino acid clusters (RAACs) for dealing with protein alignment. A two-dimensional selector was proposed for easily selecting desired RAACs with underlying biology knowledge. It is anticipated that the RaacLogo web server will play more high-potential roles for protein sequence alignment, topological estimation and protein design experiments. RaacLogo is freely available at http://bioinfor.imu.edu.cn/raaclogo.

中文翻译：

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RaacLogo：使用减少的氨基酸簇的新序列标识生成器。

序列标识在可视化一致序列中提供了快速而简洁的显示。蛋白质表现出比 DNA 更大的复杂性和多样性，这通常会影响徽标的图形表示。减少的氨基酸在简化序列比对的复杂性方面具有强大的能力，这促使我们建立了 RaacLogo。RaacLogo作为一种新的序列标识生成器，使用精简氨基酸字母表，通过选择由40多种聚类算法组成的各种精简氨基酸字母表，可以轻松生成许多为用户量身定制的不同简化标识。目前的网络服务器提供了 74 种缩减氨基酸字母表，这些字母表被手动提取以生成 673 个缩减氨基酸簇 (RAAC)，用于处理蛋白质比对。提出了一种二维选择器，用于轻松选择具有基础生物学知识的所需 RAAC。预计 RaacLogo Web 服务器将在蛋白质序列比对、拓扑估计和蛋白质设计实验中发挥更多潜在作用。RaacLogo 可在 http://bioinfor.imu.edu.cn/raaclogo 上免费获得。