A dielectric biconical antenna (DiBiCA) for radiating subnanosecond pulses to treat subcutaneous tissue was designed, constructed, and tested. It is composed of a conical wave launcher and truncated conical emitter. In between, there is a short cylinder that provides a space for a ring terminating resistor. The material of the antenna has a dielectric constant of 28, so its size is small (length: 7 cm and aperture diameter: 2.2 cm). It was housed in an oil container to withstand high voltages and avoid surface flashover. The radiated electric field, measured in water, increased as the input voltage increased up to 30 kV but leveled off for higher voltages up to 50 kV, presumably because of losses in the antenna dielectric. The maximum field was 1.5 kV/cm for a depth of 5 mm and 1.0 kV/cm for a depth of 20 mm. Although the dielectric loss mechanism remains to be investigated, the antenna can be useful for noninvasive delivery of subnanosecond pulses to induce biological responses on subcutaneous targets. The DiBiCA radiated pulses were shown to change the viabilities of dendritic cells and macrophages for 10‐min exposure. Bioelectromagnetics. 2020;41:413–424. © 2020 Bioelectromagnetics Society.

中文翻译：

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用于治疗皮下目标的高功率介电双锥天线。

设计，构造和测试了用于辐射亚纳秒脉冲以治疗皮下组织的介电双锥天线（DiBiCA）。它由锥形波发射器和截头圆锥形发射器组成。在它们之间，有一个短圆柱，为环形终端电阻器提供了空间。天线的材料的介电常数为28，因此其尺寸较小（长度：7厘米，孔径：2.2厘米）。它被装在一个油容器中，以承受高压并避免表面闪络。在水中测量的辐射电场随着输入电压增加至30 kV而增加，但对于高达50 kV的较高电压却趋于平稳，这可能是由于天线电介质的损耗所致。对于5mm的深度，最大场为1.5kV / cm，对于20mm的深度，最大场为1.0kV / cm。尽管介电损耗机制仍有待研究，但该天线可用于无创传输亚纳秒脉冲，以在皮下目标上引起生物反应。研究表明，DiBiCA辐射脉冲可改变10分钟暴露时间的树突状细胞和巨噬细胞的活力。生物电磁学。2020; 41：413-424。©2020生物电磁学会。