A comprehensive understanding of the basic molecular and cellular mechanisms of the brain is important for the scientific discovery of root causes, risk and protective factors for mental disorders in global mental health. Systematic research in cultural neuroscience within the research domain criteria (RDoC) framework investigates the fundamental biobehavioral dimensions and observable behavior across cultures. Cultural dimensions are characterized in elements of circuit-based mechanisms and behavior across a range of analysis. Research approaches in cultural neuroscience within the RDoC framework advance the evidence-based resources for the development and implementation of cures, preventions and interventions to mental disorders in global mental health. This review presents a novel synthesis of foundations in cultural neuroscience within the research domain criteria framework to advance integrative, translational efforts in discovery and delivery science of mental disorders across cultural contexts in global mental health.

全面了解大脑的基本分子和细胞机制对于科学发现全球精神健康中精神障碍的根本原因，风险和保护因素非常重要。在研究领域标准（RDoC）框架内对文化神经科学进行的系统研究研究了跨文化的基本生物行为维度和可观察的行为。文化方面的特征是在一系列分析中基于电路的机制和行为的要素。RDoC框架内的文化神经科学研究方法为全球精神卫生中精神障碍的治疗，预防和干预措施的开发和实施提供了循证资源。