Objective. Over the recent years, several small area electrodes have been introduced as tools for preferential stimulation of small cutaneous nerve fibers. However, the performance of the electrodes is highly debated and have not previously been systematically compared. The electrodes have been developed empirically and little is known about the electrical potential they produce in the skin, and how this influences the nerve fiber activation. The objective of the present study was to develop and validate a computational model to compare the preferential stimulation of small fibers for electrodes of different designs. Approach. A finite element model of the skin was developed and coupled with an A β -fiber and an A δ -fiber multi-compartmental nerve fiber model, to describe the current spread and consequent nerve fiber activation produced by five different surface electrodes; intra-epidermal, planar concentric, pin, planar array, and patch. The model was ...

中文翻译：

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比较现有电极设计以优先激活皮肤伤害感受器。

目的。近年来，已经引入了几种小面积电极作为优先刺激小皮肤神经纤维的工具。然而，电极的性能受到了激烈的争论，以前还没有被系统地比较过。电极是凭经验开发的，对其在皮肤中产生的电势及其对神经纤维激活的影响知之甚少。本研究的目的是开发和验证计算模型，以比较小纤维对不同设计电极的优先刺激。方法。建立了皮肤的有限元模型，并将其与Aβ纤维和Aδ纤维多室神经纤维模型相结合，描述由五个不同表面电极产生的电流扩散以及随之产生的神经纤维激活；表皮内，平面同心，针，平面阵列和贴片。该模型是...