当前位置：
X-MOL 学术
›
Mol. Nutr. Food Res.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Train to Lose: Innate Immune Memory in Metaflammation.
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2020-06-11 , DOI: 10.1002/mnfr.201900480 Hugo Charles-Messance 1, 2 , Frederick J Sheedy 1, 2
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2020-06-11 , DOI: 10.1002/mnfr.201900480 Hugo Charles-Messance 1, 2 , Frederick J Sheedy 1, 2
Affiliation
|
Westernized diets and lifestyle are linked to the development of metabolic syndrome, characterized by obesity, type 2 diabetes, and increased cardiovascular disease risk. Systemic low‐grade inflammation is a common feature of chronic metabolic disorders and is believed to promote disease progression. Therefore, modulating inflammation is a commonly explored strategy to prevent obesity‐associated co‐morbidities. In this review, how current knowledge on the recently described concept of innate immune memory could underline metaflammation in the context of metabolic syndrome is explored. It is hoped that these insights provide a new perspective to address the question of innate immune activation during disease progression.
中文翻译：
失去训练：Metaflammation 中的先天免疫记忆。
西化饮食和生活方式与代谢综合征的发展有关，其特征是肥胖、2 型糖尿病和心血管疾病风险增加。全身性低度炎症是慢性代谢紊乱的常见特征，被认为会促进疾病进展。因此，调节炎症是预防肥胖相关并发症的常用策略。在这篇综述中，探讨了关于最近描述的先天免疫记忆概念的当前知识如何强调代谢综合征背景下的元炎症。希望这些见解为解决疾病进展过程中的先天免疫激活问题提供了新的视角。
更新日期：2020-06-11
中文翻译：
失去训练：Metaflammation 中的先天免疫记忆。
西化饮食和生活方式与代谢综合征的发展有关，其特征是肥胖、2 型糖尿病和心血管疾病风险增加。全身性低度炎症是慢性代谢紊乱的常见特征，被认为会促进疾病进展。因此，调节炎症是预防肥胖相关并发症的常用策略。在这篇综述中，探讨了关于最近描述的先天免疫记忆概念的当前知识如何强调代谢综合征背景下的元炎症。希望这些见解为解决疾病进展过程中的先天免疫激活问题提供了新的视角。
京公网安备 11010802027423号