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Genetics of Mexico Jamiltepec Oaxaca Mixtec Amerindians according to HLA genes.
Human Immunology ( IF 3.1 ) Pub Date : 2020-06-11 , DOI: 10.1016/j.humimm.2020.05.007
Antonio Arnaiz-Villena 1 , Fabio Suarez-Trujillo 1 , Adrian Lopez-Nares 1 , Estefania Crespo-Yuste 1 , Alvaro Callado 1 , Ignacio Juarez 1
Affiliation  

Mexican Mixtec population from coastal Jamiltepec (Oaxaca) Amerindians was studied for its HLA profile. They show genetic characteristics close to Pacific Islanders and other Mexican Isthmus Amerindians (Mazatecans, Zapotecans and Mayas). Interestingly, this coastal Oaxaca Mixtec population is genetically closer to Mazatecans than to Oaxaca Mixtec from mountains according to HLA genes. Mixtec HLA frequent extended haplotype A*24:02-B*35:14-DRB1*16:02 has been also found in Jaidukama North Colombia forest Amerindians and in Guatemala Mayas; A*24:02, DRB1*04:03, DRB1*04:04 and DRB2*16:02 are frequent alleles also common to Pacific Inhabitants. Notwithstanding, Mixtecs show deep cultural and genetic roots with Mesoamerican Amerindians and all of them probably contributed to construct Monte Alban culture around an important Pyramid Complex close to Oaxaca City.



中文翻译:

根据HLA基因,墨西哥Jamiltepec Oaxaca Mixtec Amerindians的遗传学。

研究了来自沿海Jamiltepec(Oaxaca)Amerindians的墨西哥Mixtec种群的HLA谱。它们显示出接近太平洋岛民和其他墨西哥地峡美洲印第安人(马扎特人,扎波特坎人和玛雅人)的遗传特征。有趣的是,根据HLA基因,沿海Oaxaca Mixtec种群在遗传上更接近Mazatecans,而不是山区的Oaxaca Mixtec。在北哥伦比亚Jaidukama森林美洲印第安人和危地马拉玛雅人中也发现了Mixtec HLA频繁延伸的单倍型A * 24:02-B * 35:14-DRB1 * 16:02;A * 24:02,DRB1 * 04:03,DRB1 * 04:04和DRB2 * 16:02是太平洋居民常见的常见等位基因。虽然,

更新日期:2020-08-15
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