C1q/tumor necrosis factor (TNF)-related proteins (CTRPs) particularly CTRP9, have been established to be as adiponectin (APN) highly conserved paralogs which assemble several APN regulatory functions. Recently, growing body of evidences drawn significant attention to evaluate metabolic and cardiovascular effect of CTRP9. However, the potential role of CTRP9 in brain tissue has not yet fully illustrated. Here, we aimed to uncover latest advances regarding the CTRP9 related signaling pathways and during brain aging process.

中文翻译：

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CTRP9：大脑中一种新兴的潜在抗衰老分子。

C1q/肿瘤坏死因子 (TNF) 相关蛋白 (CTRP) 特别是 CTRP9，已被确定为脂联素 (APN) 高度保守的旁系同源物，其组装了多种 APN 调节功能。最近，越来越多的证据引起了人们对评估 CTRP9 代谢和心血管作用的极大关注。然而，CTRP9 在脑组织中的潜在作用尚未完全阐明。在这里，我们旨在揭示 CTRP9 相关信号通路和大脑衰老过程中的最新进展。