New coronavirus referred to SARS-CoV-2 has caused a worldwide pandemic (COVID-19) declared by WHO. Coronavirus disease 2019 (COVID-19) is an infectious disease with severe acute respiratory syndrome caused by coronavirus-2 (SARS-CoV-2). SARS-CoV-2 is akin to SARS-CoV, which was the causative agent of severe acute respiratory syndrome (SARS) in 2002 as well as to that of Middle East respiratory syndrome (MERS) in 2012. SARS-CoV-2 has been revealed to belong to Coronaviridiae family as a member of β-coronaviruses. It has a positive-sense single-stranded RNA with the largest RNA genome. Since its genomic sequence has a notable similarity to that of SARS-CoV, antiviral drugs used to treat SARS and MERS are now being also applied for COVID-19 treatment. In order to combat SARS-CoV-2, many drug and vaccine development studies at experimental and clinical levels are currently conducted worldwide. In this sense, medicinal plants and the pure natural molecules isolated from plants have been reported to exhibit significant inhibitory antiviral activity against SARS-CoV and other types of coronaviruses. In the present review, plant extracts and natural molecules with the mentioned activity are discussed in order to give inspiration to researchers to take these molecules into consideration against SARS-CoV-2.

中文翻译：

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天然产物作为对抗冠状病毒的潜在线索：它们是否可以鼓励对抗 SARS-CoV-2 的结构模型？


世界卫生组织宣布，被称为 SARS-CoV-2 的新型冠状病毒引起了全球大流行（COVID-19）。 2019 冠状病毒病 (COVID-19) 是由冠状病毒 2 (SARS-CoV-2) 引起的严重急性呼吸系统综合症传染病。 SARS-CoV-2 与 SARS-CoV 类似，后者是 2002 年严重急性呼吸综合征 (SARS) 和 2012 年中东呼吸综合征 (MERS) 的病原体。被证实属于冠状病毒科，是β冠状病毒的一员。它具有正义单链RNA，具有最大的RNA基因组。由于其基因组序列与 SARS-CoV 具有显着的相似性，用于治疗 SARS 和 MERS 的抗病毒药物现在也用于治疗 COVID-19。为了对抗SARS-CoV-2，目前世界范围内正在进行许多实验和临床水平的药物和疫苗开发研究。从这个意义上说，药用植物和从植物中分离的纯天然分子已被报道对 SARS-CoV 和其他类型的冠状病毒表现出显着的抑制抗病毒活性。在本综述中，讨论了具有上述活性的植物提取物和天然分子，以启发研究人员考虑使用这些分子来对抗 SARS-CoV-2。