Circular RNAs (circRNAs) are endogenous non-coding RNAs that form a covalently closed continuous loop, are widely distributed and play important roles in a series of developmental processes. In plants, an increasing number of studies have found that circRNAs can regulate plant metabolism and are involved in plant responses to biotic or abiotic stress. Acting as miRNA decoys is a critical way for circRNAs to perform their functions. Therefore, we developed GreenCircRNA—a database for plant circRNAs acting as miRNA decoys that is dedicated to providing a plant-based platform for detailed exploration of plant circRNAs and their potential decoy functions. This database includes over 210 000 circRNAs from 69 species of plants; the main data sources of circRNAs in this database are NCBI, EMBL-EBI and Phytozome. To investigate the function of circRNAs as competitive endogenous RNAs, the possibility of circRNAs from 38 plants to act as miRNA decoys was predicted. Moreover, we provide basic information for the circRNAs in the database, including their locations, host genes and relative expression levels, as well as full-length sequences, host gene GO (Gene Ontology) numbers and circRNA visualization. GreenCircRNA is the first database for the prediction of circRNAs that act as miRNA decoys and contains the largest number of plant species.

中文翻译：

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GreenCircRNA：充当miRNA诱饵的植物circRNA的数据库

环状RNA（circRNA）是形成共价闭合连续环的内源性非编码RNA，广泛分布并在一系列发育过程中发挥重要作用。在植物中，越来越多的研究发现circRNA可以调节植物的新陈代谢，并参与植物对生物或非生物胁迫的反应。充当miRNA诱饵是circRNA履行其职能的关键途径。因此，我们开发了GreenCircRNA，这是一个充当miRNA诱饵的植物circRNA的数据库，致力于为详细探索植物circRNA及其潜在诱饵功能的植物提供平台。该数据库包括来自69种植物的21万多个circRNA。该数据库中circRNA的主要数据来源为NCBI，EMBL-EBI和Phytozome。为了研究circRNA作为竞争性内源RNA的功能，预测了来自38种植物的circRNA充当miRNA诱饵的可能性。此外，我们提供了数据库中circRNA的基本信息，包括它们的位置，宿主基因和相对表达水平，以及全长序列，宿主基因GO（Gene Ontology）编号和circRNA可视化。GreenCircRNA是第一个预测作为miRNA诱饵的circRNA的数据库，其中包含最多的植物物种。宿主基因GO（基因本体论）编号和circRNA可视化。GreenCircRNA是第一个预测作为miRNA诱饵的circRNA的数据库，其中包含最多的植物物种。宿主基因GO（基因本体论）编号和circRNA可视化。GreenCircRNA是第一个预测作为miRNA诱饵的circRNA的数据库，其中包含最多的植物物种。