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Association between maternal serum uric acid and preeclampsia
Archives of Physiology and Biochemistry ( IF 3 ) Pub Date : 2020-06-10 , DOI: 10.1080/13813455.2020.1773863
Amir Shakarami 1 , Masoumeh Ghafarzadeh 2 , Fatemeh Yari 3 , Leila Fathi 4
Affiliation  

Abstract

Objective

The aim of this study is to compare the changes in serum uric acid levels among preeclamptic pregnant women and healthy pregnant women.

Methods

Two hundred and twenty-four (224) pregnant women were enrolled. Serum uric acid levels were analysed in the two groups at the time of referral and prior to the delivery.

Results

The mean uric acid in all pregnant women was 5.61 mg/dL. The mean uric acid in women with preeclampsia was 6.51 ± 1.53 and in normotensive women was 4.72 ± 1.58, which was seen significant. The mean age of the mother, gestational age and BMI were not significant with the levels of uric acid. The elevation in serum levels of uric acid increased the risk of preeclampsia by 1.98 folds.

Conclusion

There is a significant increase in the serum levels of uric acid in pregnant women with preeclampsia as compared to normotensive women. This can be one of a significant indicator of preeclampsia.



中文翻译:

母体血尿酸与先兆子痫的关系

摘要

客观的

本研究的目的是比较先兆子痫孕妇和健康孕妇血清尿酸水平的变化。

方法

招募了两百二十四 (224) 名孕妇。在转诊时和分娩前分析了两组的血清尿酸水平。

结果

所有孕妇的平均尿酸为 5.61 mg/dL。先兆子痫女性的平均尿酸为 6.51 ± 1.53,血压正常女性为 4.72 ± 1.58,这很显着。母亲的平均年龄、胎龄和BMI与尿酸水平不显着。血清尿酸水平的升高使先兆子痫的风险增加了 1.98 倍。

结论

与血压正常的妇女相比,先兆子痫孕妇的血清尿酸水平显着升高。这可能是先兆子痫的重要指标之一。

更新日期:2020-06-10
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