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Evaluation of the bioactive properties of Alternanthera sessilis extract and development of sodium alginate – Alternanthera sessilis membrane for wound management
Journal of Polymer Engineering ( IF 1.7 ) Pub Date : 2020-06-11 , DOI: 10.1515/polyeng-2019-0252
Ramaswamy Rajendran 1 , Mariappan Abirami 1 , Elango Santhini 2 , Selvaraj Dinesh Kirupha 2 , Ketankumar Vadodaria 2
Affiliation  

Abstract Many herbal/botanical medicines from plant sources are being used for therapeutic purpose. Alternanthera sessilis sp. plant leaves are known for their phytochemical constituents, which have potent antibacterial activity. In the present study, the properties of the A. sessilis sp. extract and the biocomposite membrane of A. sessilis sp. with sodium alginate were studied for their biomedical applications. Results showed that the A. sessilis ethanoic extract possessed high levels of antioxidant and antimicrobial activity and no cytotoxic effect under in vitro conditions. Similarly, the biocomposite membrane of alginate with the A. sessilis sp. ethanolic extract showed high antibacterial activity with hemocompatibility and swelling characteristics. Although the antioxidant, antimicrobial and cytotoxic effects of A. sessilis have been previously reported, this is the first report on the preparation of a biocomposite membrane with alginate using A. sessilis for biomedical applications.

中文翻译:

对无花果提取物的生物活性特性的评估和海藻酸钠的开发——无花果膜用于伤口处理

摘要 来自植物的许多草药/植物药被用于治疗目的。无柄互花茶 sp. 植物叶子以其植物化学成分而闻名,这些成分具有有效的抗菌活性。在本研究中,A. sessilis sp. 的特性。提取物和 A. sessilis sp. 的生物复合膜。研究了海藻酸钠的生物医学应用。结果表明,无柄木香乙醇提取物在体外条件下具有高水平的抗氧化和抗菌活性,且无细胞毒性作用。类似地,藻酸盐与 A. sessilis sp. 的生物复合膜。乙醇提取物显示出具有血液相容性和肿胀特性的高抗菌活性。尽管 A.
更新日期:2020-06-11
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