There is a general perception that any exposure to medication during pregnancy poses a potential risk to the fetus. Most available data about teratogenic drugs is derived from animal studies, case reports, or cohort studies. As a result, counseling women and their partners about the safety of drugs during pregnancy can be difficult due to limited information about efficacy, pharmacokinetics, and teratogenicity of some drugs. However, this should always be done in the context of weighing up potential teratogenic risks with the perinatal risks of an untreated medical or psychiatric condition. Ideally, this counseling should occur prior to a planned pregnancy so that medications and treatment of chronic medical conditions can be optimized. It is important that clinicians providing antenatal care are able to confidently manage women including utilizing appropriate resources. This paper aims at reviewing a selected (non‐exhaustive) list of the most commonly prescribed medications considered significant human teratogens and provides recommendations for pre‐conception and antenatal counseling.

中文翻译：

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关于母体药物相关胚胎病的最新消息。

人们普遍认为，怀孕期间接触任何药物都会对胎儿构成潜在风险。大多数关于致畸药物的可用数据来自动物研究、病例报告或队列研究。因此，由于有关某些药物的功效、药代动力学和致畸性的信息有限，就怀孕期间药物的安全性向妇女及其伴侣提供咨询可能很困难。然而，这应该始终在权衡潜在致畸风险与未经治疗的医疗或精神疾病的围产期风险的背景下进行。理想情况下，这种咨询应该在计划怀孕之前进行，以便优化慢性疾病的药物治疗和治疗。重要的是，提供产前保健的临床医生能够自信地管理妇女，包括利用适当的资源。本文旨在审查被认为是显着人类致畸剂的最常用处方药的选定（非详尽）清单，并为受孕前和产前咨询提供建议。