Valproic acid (VPA) is a broad‐spectrum antiepileptic drug. It has been widely used in bipolar disorder treatment for many years. Although treatment is generally well tolerated, serious complications such as hemorrhagic pancreatitis, bone marrow suppression, hepatotoxicity and encephalopathy can occur. Because of bilateral opacity consistent with pulmonary edema, hypoxemia, increased venous admixture and increased lung compliance, patients with ARDS need oxygen care and supportive care in the intensive care unit.

中文翻译：

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重症监护病房中丙戊酸毒性后的急性呼吸窘迫综合征（ARDS）：病例报告。

丙戊酸（VPA）是一种广谱抗癫痫药。多年来，它已广泛用于双相情感障碍治疗。尽管通常耐受性良好，但可能发生严重并发症，例如出血性胰腺炎，骨髓抑制，肝毒性和脑病。由于双侧浑浊与肺水肿，低氧血症，静脉混合增加以及肺顺应性一致，ARDS患者需要在重症监护病房进行氧气治疗和支持治疗。