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The Entamoeba lysine and glutamic acid rich protein (KERP1) virulence factor gene is present in the genomes of Entamoeba nuttalli, Entamoeba dispar and Entamoeba moshkovskii.
Molecular and Biochemical Parasitology ( IF 1.4 ) Pub Date : 2020-06-11 , DOI: 10.1016/j.molbiopara.2020.111293
Gareth D Weedall 1
Affiliation  

The lysine and glutamic acid rich protein KERP1 is a cell surface-expressed virulence factor in the human pathogen Entamoeba histolytica. It was originally suggested that the gene was absent from the related, avirulent human commensal Entamoeba dispar, an absence which would be relevant to the differential virulence of these species. Here, the gene is shown to be present in E. dispar, and its sequence is presented, as well as in a virulent parasite of macaques, Entamoeba nuttalli, and the primarily free living, opportunistically parasitic Entamoeba moshkovskii.



中文翻译:

Entamoeba赖氨酸和谷氨酸富含蛋白(KERP1)毒力因子基因存在于Entamoeba nuttalli,Entamoeba dispar和Entamoeba moshkovskii的基因组中。

赖氨酸和谷氨酸丰富的蛋白质KERP1是人类病原体Entamoeba histolytica中细胞表面表达的毒力因子。最初有人提出该基因在相关的无毒人类共患病肠轮虫中不存在,而缺失与这些物种的不同毒力有关。在这里,该基因显示存在于E. dispar中,并显示了其序列,以及在猕猴的致病性寄生虫Entamoeba nuttalli和主要的自由生活,机会性寄生虫Entamoeba moshkovskii中

更新日期:2020-06-11
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