Background

Peritoneal dissemination of ovarian immature teratoma in children is a rare entity and is associated with a poor prognosis. There are no guidelines on the optimal management of these patients with regard to surgery and systemic treatments.

Case

This is the case of a 16-year-old patient who experienced an early recurrence of immature teratoma with peritoneal dissemination after surgery and systemic chemotherapy failure, and was treated with an aggressive salvage cytoreductive surgery. She was still disease-free 6 months after her second surgery.

Summary and Conclusion

Upfront aggressive surgical management with complete cytoreductive surgery is recommended when patients present with disease recurrence and peritoneal dissemination of ovarian immature teratoma. Such cases should be managed in centers with local expertise in the treatment of peritoneal surface malignancies.

中文翻译：

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复发性高级卵巢未成熟畸胎瘤伴腹膜扩散。

背景

小儿卵巢未成熟畸胎瘤的腹膜扩散是一种罕见的现象，与预后不良有关。没有关于这些患者在手术和全身治疗方面的最佳治疗的指南。

案件

这是一名16岁患者的案例，该患者在手术和全身化疗失败后经历了不成熟畸胎瘤的早期复发并腹膜扩散，并接受了积极的抢救性细胞减灭术治疗。第二次手术六个月后，她仍然没有病。

总结与结论

当患者出现疾病复发和卵巢未成熟畸胎瘤的腹膜扩散时，建议先行积极的外科手术处理并进行彻底的细胞减灭术。此类病例应在具有腹膜表面恶性肿瘤治疗本地经验的中心进行管理。