Introduction

The ansa peduncularis is a composite of white matter fiber bundles closely packed together that sweeps around the cerebral peduncle. The exact components of the ansa peduncularis and their anatomical trajectories are still not established firmly in the literature.

Objective

The aim of this study was to examine the topographical anatomy of the ansa peduncularis and its subcomponents using the fiber dissection and tractography techniques.

Methods

Ten formalin-fixed brains were prepared according to Klingler’s method and dissected by the fiber dissection technique from the lateral, medial and inferior surfaces. The ansa peduncularis was also traced using high definition fiber tracking (HDFT) from the MRI data of twenty healthy adults and a 1021-subject template from the Human Connectome Project.

Results

The ventral amygdalofugal pathway system includes white matter fiber bundles with a topographically close relation as they sweep around the cerebral peduncle and contribute to form the ansa peduncularis: amygdaloseptal fibers connect the amygdala and anterior temporal cortex to the septal region and amygdalohypothalamic fibers project from the amygdala to the hypothalamus. Additionally, from the amygdala and anterior temporal cortex, amygdalothalamic fibers project to the medial thalamic region. The ansa lenticularis, which connects the globus pallidus to the thalamus, was not shown in our study.

Conclusion

The study demonstrated the trajectory of the ansa peduncularis and its subcomponents, based on fiber dissection and tractography, improving our understanding of human brain anatomical connectivity.

中文翻译：

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人脑中的马蹄莲：纤维束成像和纤维解剖研究。

介绍

Ansa peduncularis 是一种由紧密堆积在一起的白质纤维束组成的复合物，它环绕着大脑脚。Ansa peduncularis 的确切组成部分及其解剖轨迹在文献中仍未确定。

客观的

本研究的目的是使用纤维解剖和纤维束成像技术检查马蹄莲及其子组件的地形解剖结构。

方法

根据 Klingler 的方法制备十个福尔马林固定的大脑，并通过纤维解剖技术从外侧、内侧和下表面解剖。还使用来自 20 名健康成年人的 MRI 数据和来自人类连接组项目的 1021 个受试者模板的高清纤维跟踪 (HDFT) 追踪了足柄蝽。

结果

腹侧杏仁核通路系统包括白质纤维束，它们在脑脚周围扫过并有助于形成脚柄：杏仁核中隔纤维将杏仁核和前颞叶皮层连接到间隔区域，杏仁核下丘脑纤维从杏仁核突出到下丘脑。此外，杏仁核纤维从杏仁核和前颞叶皮层投射到内侧丘脑区域。我们的研究中没有显示连接苍白球和丘脑的扁豆状体。

结论

该研究基于纤维解剖和纤维束成像，展示了足柄蕈及其子成分的轨迹，提高了我们对人脑解剖学连通性的理解。