The recent COVID-19 pandemic has had a significant impact on our lives and has rapidly expanded to reach more than 4 million cases worldwide by May 2020. These cases are characterized by extreme variability, from a mild or asymptomatic form lasting for a few days up to severe forms of interstitial pneumonia that may require ventilatory therapy and can lead to patient death.

Several hypotheses have been drawn up to understand the role of the interaction between the infectious agent and the immune system in the development of the disease and the most severe forms; the role of the cytokine storm seems important.

Innate immunity, as one of the first elements of guest interaction with different infectious agents, could play an important role in the development of the cytokine storm and be responsible for boosting more severe forms. Therefore, it seems important to study also this important arm of the immune system to adequately understand the pathogenesis of the disease. Research on this topic is also needed to develop therapeutic strategies for treatment of this disease.

最近的 COVID-19 大流行对我们的生活产生了重大影响，到 2020 年 5 月，全球病例已迅速扩大到超过 400 万例。这些病例的特点是变异性极大，从轻微或无症状的形式持续几天到最多的时间严重的间质性肺炎可能需要通气治疗并可能导致患者死亡。

为了了解传染源和免疫系统之间的相互作用在疾病发展和最严重形式中的作用，人们提出了几种假设；细胞因子风暴的作用似乎很重要。

先天免疫作为客体与不同传染源相互作用的首要因素之一，可能在细胞因子风暴的发展中发挥重要作用，并负责促进更严重的形式。因此，研究免疫系统的这一重要分支以充分了解该疾病的发病机制似乎很重要。还需要对此主题进行研究来制定治疗这种疾病的治疗策略。