Background Nearly one-third of epilepsy patients are refractory/resistant to medical treatment. Developments made in surgical techniques have significantly increased the effectiveness and safety of these techniques, as such techniques have been demonstrated to improve seizure control/freedom outcomes. Objectives The aim of this systematic review and meta-analysis was to evaluate the complications of epilepsy surgery. Patient and methods The searches were conducted by three independent researchers to find the relevant studies published from January 1, 2009, until the end of January 6, 2019. For English published statistical studies, all studies conducted on epileptic patients who have undergone epilepsy surgery were included. Statistical analysis A meta-analysis was conducted in the STATA14 statistical software. Results A total of 6735 patients with epilepsy who had undergone the epilepsy surgery were studied. The overall prevalence of complications was 5%. The prevalence of major and minor complications was 5.4% and 3.2% respectively. The prevalence of complications related to the temporal epilepsy surgery and the extra-temporal epilepsy surgery based on 3 studies was 7.9% and 8.2 % respectively. The frequency of neurological and surgical complications after epilepsy surgery was 4.4% and 4.1% respectively. Conclusion The overall rate of complications caused by epilepsy surgery was reasonably low (5%), implying that epilepsy surgery especially temporal lobe resection can be safe preferably when performed by an experienced surgeon.

中文翻译：

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难治性癫痫的癫痫手术：不同并发症的系统评价和荟萃分析

背景 近三分之一的癫痫患者对药物治疗具有难治性/耐药性。外科技术的发展显着提高了这些技术的有效性和安全性，因为这些技术已被证明可以改善癫痫发作控制/自由结果。目的 本系统评价和荟萃分析的目的是评估癫痫手术的并发症。患者和方法 搜索由三位独立研究人员进行，以查找从 2009 年 1 月 1 日至 2019 年 1 月 6 日期间发表的相关研究。对于英文发表的统计研究，所有对接受癫痫手术的癫痫患者进行的研究均为包括。统计分析 在 STATA14 统计软件中进行了荟萃分析。结果共研究了6735例接受过癫痫手术的癫痫患者。并发症的总体患病率为 5%。主要和次要并发症的患病率分别为 5.4% 和 3.2%。根据 3 项研究，颞叶癫痫手术和颞外癫痫手术相关并发症的发生率分别为 7.9% 和 8.2%。癫痫手术后神经系统和手术并发症的发生率分别为 4.4% 和 4.1%。结论 癫痫手术引起的总体并发症发生率相当低（5%），表明癫痫手术尤其是颞叶切除术在有经验的外科医生进行时是安全的。主要和次要并发症的患病率分别为 5.4% 和 3.2%。根据 3 项研究，颞叶癫痫手术和颞外癫痫手术相关并发症的发生率分别为 7.9% 和 8.2%。癫痫手术后神经系统和手术并发症的发生率分别为 4.4% 和 4.1%。结论 癫痫手术引起的总体并发症发生率相当低（5%），表明癫痫手术尤其是颞叶切除术在有经验的外科医生进行时是安全的。主要和次要并发症的患病率分别为 5.4% 和 3.2%。根据 3 项研究，颞叶癫痫手术和颞外癫痫手术相关并发症的发生率分别为 7.9% 和 8.2%。癫痫手术后神经系统和手术并发症的发生率分别为 4.4% 和 4.1%。结论 癫痫手术引起的总体并发症发生率相当低（5%），这意味着癫痫手术尤其是颞叶切除术在有经验的外科医生进行时是安全的。癫痫手术后神经系统和手术并发症的发生率分别为 4.4% 和 4.1%。结论 癫痫手术引起的总体并发症发生率相当低（5%），表明癫痫手术尤其是颞叶切除术在有经验的外科医生进行时是安全的。癫痫手术后神经系统和手术并发症的发生率分别为 4.4% 和 4.1%。结论 癫痫手术引起的总体并发症发生率相当低（5%），表明癫痫手术尤其是颞叶切除术在有经验的外科医生进行时是安全的。