This study was aimed at evaluating the hematinic effect of Spondias mombin and its protective role against the spleenotoxic effect of Phenylhydrazine (PHZ). Thirty Wistar rats were randomized into 6 groups. Group A (Control) animals were neither given the extract nor PHZ. Rats in groups B and C were administered 150 mg/kg body weight and 300 mg/kg body weight doses of the extract respectively. Anemia was induced in rats in groups D and E by oral administration of 40 mg/kg body weight of PHZ and concomitantly administered 150 mg/kg body weight and 300 mg/kg body weight doses of the extract respectively. Anemia was also induced in rats in group F by administration of 40 mg/kg body weight of PHZ but without administration of the extract. Histology of the spleen show moderate expansion of the red pulp and contraction of lymphoid follicles in group F and mild follicular activation and sinus histiocytosis in group D. There were significant (p < 0.05) increase in the weight of the spleen in group F and decrease in group C. Results also show significant (p < 0.05) decreases in the RBC count in group F and increases in the Mean Corpuscular Volume and Mean Corpuscular Haemoglobin in groups D and E. There was also a significant (P < 0.05) decrease in the Mean Corpuscular Haemoglobin Count in group D. This study shows the hematinic effect of Spondias mombin and its possible use in ethno-medicine in managing anemic conditions, as well as its potential in protecting against the spleenotoxic effect of PHZ.

中文翻译：

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补血的效果黄酸枣和其对苯的spleenotoxic效果保护作用

这项研究的目的是评估印度洋槐的血红蛋白作用及其对苯肼（PHZ）的脾毒性作用的保护作用。将30只Wistar大鼠随机分为6组。A组（对照）动物均未给予提取物或PHZ。B组和C组的大鼠分别服用150 mg / kg体重和300 mg / kg体重的提取物。在D组和E组的大鼠中，通过口服给予40mg / kg体重的PHZ并同时给予150mg / kg体重和300mg / kg体重的提取物来诱发贫血。通过给予40 mg / kg体重的PHZ，但不给予提取物，也可以在F组大鼠中诱发贫血。