The human turbinate-derived mesenchymal stem cells (hTMSCs), which were DiI-labeled and transplanted into the subretinal space in degenerating mouse retina, were observed in retinal vertical sections processed for rhodopsin (a marker for rod photoreceptor) by confocal microscope with differential interference contrast (DIC) filters. The images clearly demonstrated that DiI-labeled hTMSCs have rhodopsin-immunoreactive appendages, indicating differentiation of transplanted hTMSC into rod photoreceptor. Conclusively, the finding suggests therapeutic potential of hTMSCs in retinal degeneration.

中文翻译：

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小鼠退化性视网膜从移植的下鼻甲干细胞分化为杆状光感受器的体内分化的光学显微镜证据

人鼻甲源性间充质干细胞 (hTMSCs) 被 DiI 标记并移植到退化小鼠视网膜的视网膜下空间，在视紫质（杆状光感受器的标记物）处理的视网膜垂直切片中通过微分干涉共聚焦显微镜观察对比 (DIC) 过滤器。图像清楚地表明，DiI 标记的 hTMSCs 具有视紫质免疫反应性附属物，表明移植的 hTMSC 分化为杆状光感受器。最后，这一发现表明 hTMSCs 在视网膜变性中的治疗潜力。