Soybeans are used worldwide as food and as a healthy ingredient. Specifically, soy germ (SG) has received considerable attention owing to its abundant nutritional and biological components. This study aimed to elucidate the contents of isoflavone and soyasaponin of SG in 24 Korean soybean cultivars and the osteogenic activity of individual compounds. The isoflavone content in the SG ranged from 1110.9 to 3131.1 mg/100 g, and the soyasaponin content in SG ranged from 1173.5 to 3582.3 mg/100 g. The isoflavone and soyasaponin content depended on soybean cultivars. All isoflavone and soyasaponin compounds enhanced bone morphogenetic protein-2-mediated osteoblast differentiation in a dose-dependent manner, especially soyasaponin Ab. In conclusion, our results suggest that Seonpung cultivar with high soyasaponin Ab is beneficial for developing functional materials.

中文翻译：

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韩国大豆[ Glycine max（L.）Merr。]品种细菌中的异黄酮和大豆皂苷及其复合增强的BMP-2诱导的骨形成

大豆在世界范围内被用作食品和健康成分。特别是，大豆胚芽（SG）由于其丰富的营养和生物成分而受到了广泛的关注。本研究旨在阐明韩国24个大豆品种中SG的异黄酮和大豆皂苷的含量以及单个化合物的成骨活性。SG中的异黄酮含量范围为1110.9至3131.1 mg / 100 g，SG中的大豆皂甙含量范围为1173.5至3582.3 mg / 100 g。异黄酮和大豆皂苷的含量取决于大豆品种。所有异黄酮和大豆皂苷化合物均以剂量依赖性方式增强骨形态发生蛋白2介导的成骨细胞分化，特别是大豆皂苷Ab。结论，