Background: Recent respiratory infection including SARS-CoV-2 is an independent risk factor for acute cerebrovascular disease. Purpose: There have been reports linking haemorrhagic strokes to SARS-CoV-2 infection during this pandemic, which lead us to evaluate if SARS-CoV-2 infection could be associated with increased risk of intracerebral haemorrhage (ICH). Methods: A retrospective observational study evaluating all stroke cases admitted in our centre in the past one month. Results: More than half (56%) had ICH, compared to 22% last year. Two patients with ICH were SARS-CoV-2 positive and they had no or mild respiratory symptoms and had higher occurrence of renal dysfunction. Conclusion: There could be possible association between ICH and SARS-CoV-2 infections. However, a prospective study with larger sample size is needed to elucidate the pathogenesis.


中文翻译：

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脑出血和 SARS-CoV-2：关联或因果关系。


背景：包括 SARS-CoV-2 在内的近期呼吸道感染是急性脑血管疾病的独立危险因素。目的：有报道称，在这次大流行期间，出血性中风与 SARS-CoV-2 感染有关，这促使我们评估 SARS-CoV-2 感染是否与脑出血 (ICH) 风险增加有关。方法：一项回顾性观察研究评估了过去一个月内我中心收治的所有卒中病例。结果：超过一半 (56%) 患有 ICH，而去年这一比例为 22%。两名 ICH 患者为 SARS-CoV-2 阳性，他们没有或有轻微的呼吸道症状，肾功能不全的发生率较高。结论：ICH 和 SARS-CoV-2 感染之间可能存在关联。然而，需要更大样本量的前瞻性研究来阐明发病机制。